Author’s response to reviews Title: Prolonged Preoperative Treatment of Acromegaly with Somatostatin Analogs May improve Surgical Outcome in Patients with Invasive Pituitary Macroadenoma (Knosp grades 1 3): A Retrospective Cohort Study conducted at a Single Center Authors:
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چکیده
Title: Prolonged Preoperative Treatment of Acromegaly with Somatostatin Analogs May improve Surgical Outcome in Patients with Invasive Pituitary Macroadenoma (Knosp grades 1 3): A Retrospective Cohort Study conducted at a Single Center Authors: Lian Duan ([email protected]) Huijuan Zhu ([email protected]) Bing Xing ([email protected]) Feng Gu ([email protected]) Version: 1 Date: 2017-06-02 Author’s response to reviews: Manuscript ID: BEND-D-17-00031 Title: Prolonged Preoperative Treatment of Acromegaly with Somatostatin Analogs May improve Surgical Outcome in Patients with Invasive Pituitary Macroadenoma: A Retrospective Cohort Study conducted at a Single Center Journal: BMC Endocrine Disorders
منابع مشابه
Prolonged preoperative treatment of acromegaly with Somatostatin analogs may improve surgical outcome in patients with invasive pituitary macroadenoma (Knosp grades 1–3): a retrospective cohort study conducted at a single center
BACKGROUND This study aimed to investigate preoperative somatostatin analogs (SSAs) treatment on the surgical outcome in patients with acromegaly. METHODS An analysis of 358 patients with acromegaly was conducted. The preoperative medical therapy group (81 patients) received SSA treatment for at least 3 months prior to surgery, while the primary surgery group (277 patients) underwent transsph...
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CONTEXT Transsphenoidal neurosurgery is the accepted first-line treatment of acromegaly in the majority of patients. Previous studies addressing preoperative somatostatin analog (SSA) treatment and subsequent surgical cure rates are conflicting, reporting either benefits or no significant differences. OBJECTIVE The aim of this study, based on a meta-analysis of all published reports, was to i...
متن کاملPreoperative somatostatin analogs treatment in acromegalic patients with macroadenomas. A meta-analysis.
BACKGROUND Several studies have investigated the biochemical remission rate of presurgical somatostatin analogs treatment on acromegaly, but the remission criteria were diversed and the results were contradicting. OBJECTIVE Aim of this paper is to provide enhanced evidence for the effectiveness of preoperative SSA treatment to improve on surgical results of macroadenomas in acromegaly. DATA...
متن کاملGross total resection or debulking of pituitary adenomas improves hormonal control of acromegaly by somatostatin analogs.
INTRODUCTION Invasive GH-secreting pituitary adenomas are rarely cured by surgery and although long-term therapy with somatostatin analogs (SSAs) may be employed, hormonal control is achieved in only 60% of cases. The impact of tumor debulking on subsequent control of acromegaly with SSAs has not been studied previously. METHODS We studied retrospectively the response to SSA therapy in acrome...
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Background: Giant cell tumor (GCT) of the bone is a benign neoplasm with local aggressive behavior. Distal ulna is a very rare place for GCT. Published studies have mainly focused on case reports, and thus there is no consistent treatment strategy for this tumor at this location. This retrospective study was conducted to evaluate the oncological and functional results of 2 di...
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